Calpol 650: A Comprehensive Guide to Dosage and Uses


When it comes to managing pain and fever in adults, Calpol 650 is a popular over-the-counter medication that many people turn to. This medication contains paracetamol, also known as acetaminophen, which is widely used for its analgesic (pain-relieving) and antipyretic (fever-reducing) properties. In this comprehensive guide, we will delve into the dosage recommendations, uses, side effects, and precautions associated with Calpol 650.

Dosage Recommendations

  • For Adults: The typical dose for adults is 500 mg to 1000 mg every 4 to 6 hours as needed. However, the maximum dose should not exceed 4000 mg in a 24-hour period. Calpol 650 contains 650 mg of paracetamol in each tablet, making it a convenient option for adult dosing.

  • For Elderly Individuals: It is advisable for older adults to start with the lowest effective dose of Calpol 650 and not exceed the maximum daily limit of 4000 mg.

  • For Liver or Kidney Impairment: In individuals with liver or kidney dysfunction, a lower dose of Calpol 650 may be recommended. It is essential to consult a healthcare provider for personalized dosing guidance in such cases.

Uses of Calpol 650

  1. Pain Relief: Calpol 650 is commonly used to alleviate mild to moderate pain, including headaches, muscular aches, toothaches, and menstrual cramps.

  2. Fever Reduction: It is effective in reducing fever associated with various conditions such as infections, flu, and other illnesses.

  3. Arthritis: Calpol 650 can provide relief from pain and inflammation in individuals suffering from arthritis or joint pains.

  4. Post-Surgical Pain: It is often prescribed by healthcare professionals to manage post-operative pain.

  5. Migraines: Calpol 650 can be used to alleviate the pain and discomfort associated with migraines.

Side Effects and Precautions

While Calpol 650 is generally considered safe when taken as directed, it is essential to be aware of potential side effects and precautions:

  • Upset Stomach: Some individuals may experience stomach upset or nausea when taking Calpol 650. Taking the medication with food can help minimize these side effects.

  • Allergic Reactions: Rarely, allergic reactions such as skin rashes, swelling, or difficulty breathing may occur. Seek immediate medical attention if you experience any signs of an allergic reaction.

  • Liver Damage: Exceeding the recommended dose of Calpol 650 can lead to liver damage. It is crucial to adhere to the dosing guidelines and avoid combining this medication with alcohol, which can further stress the liver.

  • Avoid Overdosing: Overdosing on paracetamol can have serious consequences, including liver failure. If you suspect an overdose, seek immediate medical help.

Frequently Asked Questions (FAQs)

  1. Can I take Calpol 650 on an empty stomach?
    It is generally safe to take Calpol 650 on an empty stomach; however, if you experience stomach upset, consider taking it with food.

  2. Can I drink alcohol while taking Calpol 650?
    It is advisable to avoid alcohol when taking Calpol 650 as it can increase the risk of liver damage.

  3. Is Calpol 650 safe for pregnant women?
    Pregnant women should consult their healthcare provider before taking Calpol 650 to ensure it is safe for their specific situation.

  4. Can Calpol 650 be given to children?
    Calpol 650 is formulated for adult use. For children, it’s essential to use age-appropriate formulations and dosages.

  5. How long can I take Calpol 650 for?
    It is recommended not to use Calpol 650 for more than a few days for pain relief or fever reduction without consulting a healthcare provider.

  6. What should I do if I miss a dose of Calpol 650?
    If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

  7. Can I take Calpol 650 if I have a history of liver disease?
    Individuals with a history of liver disease should use Calpol 650 with caution and under the guidance of a healthcare provider to prevent complications.

  8. Does Calpol 650 interact with other medications?
    Calpol 650 may interact with certain medications, including blood thinners and certain antibiotics. Inform your healthcare provider about all the medications you are taking before starting Calpol 650.

  9. What should I do if I experience side effects from Calpol 650?
    If you experience severe side effects such as difficulty breathing, chest pain, or severe skin reactions, seek immediate medical attention. For mild side effects, consult your healthcare provider for guidance.

  10. Can I take Calpol 650 for chronic pain management?
    Calpol 650 is not intended for long-term use in chronic pain management. If you require pain relief on a regular basis, discuss alternative treatment options with your healthcare provider.


In conclusion, Calpol 650 is a widely used medication for pain relief and fever reduction in adults. By understanding the appropriate dosage, uses, side effects, and precautions associated with Calpol 650, individuals can use this medication safely and effectively. It is crucial to follow the recommended dosing guidelines, be aware of potential side effects, and consult a healthcare provider if needed. Remember, when in doubt, always seek medical advice before starting or adjusting any medication regimen.

Leave a Reply

Your email address will not be published. Required fields are marked *